Intra-Tumoral Pharmacokinetics of Pazopanib in Combination with Radiotherapy in Patients with Non-Metastatic Soft-Tissue Sarcoma

SIMPLE SUMMARY: Pazopanib plasma levels have been associated with treatment efficacy. Since pazopanib targets receptors present on cells in the vicinity of the tumor and on tumor cells themselves, measurement of pazopanib concentrations in tumor tissue might be an even better prognostic biomarker th...

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Detalles Bibliográficos
Autores principales: Molenaar-Kuijsten, Laura, van Meekeren, Milan, Verheijen, Remy B., Bovée, Judith V. M. G., Fiocco, Marta, Thijssen, Bas, Rosing, Hilde, Huitema, Alwin D. R., Miah, Aisha B., Gelderblom, Hans, Haas, Rick L. M., Steeghs, Neeltje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616484/
https://www.ncbi.nlm.nih.gov/pubmed/34830931
http://dx.doi.org/10.3390/cancers13225780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616484/
https://www.ncbi.nlm.nih.gov/pubmed/34830931
http://dx.doi.org/10.3390/cancers13225780

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