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Amyloid-Beta Peptides and Activated Astroglia Impairs Proliferation of Nerve Growth Factor Releasing Cells In Vitro: Implication for Encapsulated Cell Biodelivery-Mediated AD Therapy

Alzheimer’s disease (AD) treatment is constrained due to the inability of peripherally administered therapeutic molecules to cross the blood–brain barrier. Encapsulated cell biodelivery (ECB) devices, a tissue-targeted approach for local drug release, was previously optimized for human mature nerve...

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Detalles Bibliográficos
Autores principales: Mitra, Sumonto, Turchetto, Silvia, Van Os, Winant, Wahlberg, Lars U., Linderoth, Bengt, Behbahani, Homira, Eriksdotter, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616486/
https://www.ncbi.nlm.nih.gov/pubmed/34831056
http://dx.doi.org/10.3390/cells10112834