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Dysregulation of Caveolin-1 Phosphorylation and Nuclear Translocation Is Associated with Senescence Onset

We recently reported that the inability of osteoarthritic (OA) chondrocytes to repair oxidative stress (OS) induced DNA damage is linked to Cav-1 overexpression/improper localization. We speculated that the senescent status of OA cells was responsible for this Cav-1 dysregulation. Here, to further i...

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Detalles Bibliográficos
Autores principales: Goutas, Andreas, Outskouni, Zozo, Papathanasiou, Ioanna, Satra, Maria, Koliakos, George, Trachana, Varvara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616550/
https://www.ncbi.nlm.nih.gov/pubmed/34831162
http://dx.doi.org/10.3390/cells10112939