Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood

Inflammasome activation is linked to the aggregation of the adaptor protein ASC into a multiprotein complex, known as the ASC speck. Redistribution of cytosolic ASC to this complex has been widely used as a readout for inflammasome activation and precedes the downstream proteolytic release of the pr...

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Detalles Bibliográficos
Autores principales: Wittmann, Nico, Behrendt, Ann-Kathrin, Mishra, Neha, Bossaller, Lukas, Meyer-Bahlburg, Almut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616555/
https://www.ncbi.nlm.nih.gov/pubmed/34831104
http://dx.doi.org/10.3390/cells10112880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616555/
https://www.ncbi.nlm.nih.gov/pubmed/34831104
http://dx.doi.org/10.3390/cells10112880

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