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Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Inflammasome activation is linked to the aggregation of the adaptor protein ASC into a multiprotein complex, known as the ASC speck. Redistribution of cytosolic ASC to this complex has been widely used as a readout for inflammasome activation and precedes the downstream proteolytic release of the pr...
Autores principales: | Wittmann, Nico, Behrendt, Ann-Kathrin, Mishra, Neha, Bossaller, Lukas, Meyer-Bahlburg, Almut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616555/ https://www.ncbi.nlm.nih.gov/pubmed/34831104 http://dx.doi.org/10.3390/cells10112880 |
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