MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea

Failure in the structural maintenance of the hair cell stereocilia bundle and ribbon synapse causes hearing loss. Here, we have studied how ER stress elicits hair cell pathology, using mouse models with inactivation of Manf (mesencephalic astrocyte-derived neurotrophic factor), encoding an ER-homeos...

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Detalles Bibliográficos
Autores principales: Ikäheimo, Kuu, Herranen, Anni, Iivanainen, Vilma, Lankinen, Tuuli, Aarnisalo, Antti A, Sivonen, Ville, Patel, Kashyap A, Demir, Korcan, Saarma, Mart, Lindahl, Maria, Pirvola, Ulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616558/
https://www.ncbi.nlm.nih.gov/pubmed/34815294
http://dx.doi.org/10.26508/lsa.202101068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616558/
https://www.ncbi.nlm.nih.gov/pubmed/34815294
http://dx.doi.org/10.26508/lsa.202101068

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