Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease

In Alzheimer´s disease (AD) there is a reduction in hippocampal neurogenesis that has been associated to cognitive deficits. Previously we showed that Andrographolide (ANDRO), the main bioactive component of Andrographis paniculate, induces proliferation in the hippocampus of the APPswe/PSEN1ΔE9 (AP...

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Detalles Bibliográficos
Autores principales: Arredondo, Sebastian B., Reyes, Daniel T., Herrera-Soto, Andrea, Mardones, Muriel D., Inestrosa, Nibaldo C., Varela-Nallar, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616902/
https://www.ncbi.nlm.nih.gov/pubmed/34824314
http://dx.doi.org/10.1038/s41598-021-01977-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616902/
https://www.ncbi.nlm.nih.gov/pubmed/34824314
http://dx.doi.org/10.1038/s41598-021-01977-x

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