A structured RNA motif locks Argonaute2:miR-122 onto the 5’ end of the HCV genome

microRNAs (miRNAs) form regulatory networks in metazoans. Viruses engage miRNA networks in numerous ways, with Flaviviridae members exploiting direct interactions of their RNA genomes with host miRNAs. For hepatitis C virus (HCV), binding of liver-abundant miR-122 stabilizes the viral RNA and regula...

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Detalles Bibliográficos
Autores principales: Gebert, Luca F. R., Law, Mansun, MacRae, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616905/
https://www.ncbi.nlm.nih.gov/pubmed/34824224
http://dx.doi.org/10.1038/s41467-021-27177-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616905/
https://www.ncbi.nlm.nih.gov/pubmed/34824224
http://dx.doi.org/10.1038/s41467-021-27177-9

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