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STAT3 is critical for skeletal development and bone homeostasis by regulating osteogenesis

Skeletal deformities are typical AD-HIES manifestations, which are mainly caused by heterozygous and loss-of-function mutations in Signal transducer and activator of transcription 3 (STAT3). However, the mechanism is still unclear and the treatment strategy is limited. Herein, we reported that the m...

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Detalles Bibliográficos
Autores principales: Zhou, Siru, Dai, Qinggang, Huang, Xiangru, Jin, Anting, Yang, Yiling, Gong, Xinyi, Xu, Hongyuan, Gao, Xin, Jiang, Lingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616950/
https://www.ncbi.nlm.nih.gov/pubmed/34824272
http://dx.doi.org/10.1038/s41467-021-27273-w