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Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages

Spinal ependymomas are the most common spinal cord tumors in adults, but their intratumoral cellular heterogeneity has been less studied, and how spinal microglia are involved in tumor progression is still unknown. Here, our single-cell RNA-sequencing analyses of three spinal ependymoma subtypes dis...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Cheng, Sijin, Wang, Yongzhi, Wang, Mengdi, Lu, Yufeng, Wen, Zengqi, Ge, Yuxin, Ma, Qiang, Chen, Youqiao, Zhang, Yaowu, Cao, Ren, Li, Min, Liu, Weihao, Wang, Bo, Wu, Qian, Jia, Wenqing, Wang, Xiaoqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617028/
https://www.ncbi.nlm.nih.gov/pubmed/34824203
http://dx.doi.org/10.1038/s41467-021-27018-9