Development of a self-limiting model of methotrexate-induced mucositis reinforces butyrate as a potential therapy

Gastrointestinal mucositis is a complication of anticancer treatment, with few validated in vitro systems suitable to study the complex mechanisms of mucosal injury. Therefore, we aimed to develop and characterize a chemotherapeutic-induced model of mucositis using 3D intestinal organoids. Organoids...

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Detalles Bibliográficos
Autores principales: da Silva Ferreira, A. R., van der Aa, S. A. J., Wehkamp, T., Wardill, H. R., ten Klooster, J. P., Garssen, J., Harthoorn, L. F., Hartog, A., Harmsen, H. J. M., Tissing, W. J. E., van Bergenhenegouwen, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617074/
https://www.ncbi.nlm.nih.gov/pubmed/34824316
http://dx.doi.org/10.1038/s41598-021-02308-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617074/
https://www.ncbi.nlm.nih.gov/pubmed/34824316
http://dx.doi.org/10.1038/s41598-021-02308-w

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