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Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A
HIV-1 Vpr is a prototypic member of a large family of structurally related lentiviral virulence factors that antagonize various aspects of innate antiviral immunity. It subverts host cell DNA repair and protein degradation machineries by binding and inhibiting specific post-replication repair enzyme...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617076/ https://www.ncbi.nlm.nih.gov/pubmed/34824204 http://dx.doi.org/10.1038/s41467-021-27009-w |