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Receptor depletion and recovery in small-intestinal neuroendocrine tumors and normal tissues after administration of a single intravenous dose of octreotide measured by (68)Ga-DOTATOC PET/CT

BACKGROUND: Low-grade neuroendocrine tumors (NETs) are characterized by an abundance of somatostatin receptors (SSTR) that can be targeted with somatostatin analogs (SSA). When activated with a single dose of SSA, the receptor-ligand complex is internalized, and the receptor is by default recycled w...

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Detalles Bibliográficos
Autores principales: Jahn, Ulrika, Ilan, Ezgi, Velikyan, Irina, Fröss-Baron, Katarzyna, Lubberink, Mark, Sundin, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617112/
https://www.ncbi.nlm.nih.gov/pubmed/34822040
http://dx.doi.org/10.1186/s13550-021-00860-0