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Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation

Integration of external signals and B-lymphoid transcription factor activities organise B cell lineage commitment through alternating cycles of proliferation and differentiation, producing a diverse repertoire of mature B cells. We use single-cell transcriptomics/proteomics to identify differentiall...

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Detalles Bibliográficos
Autores principales: Lee, Robin D., Munro, Sarah A., Knutson, Todd P., LaRue, Rebecca S., Heltemes-Harris, Lynn M., Farrar, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617197/
https://www.ncbi.nlm.nih.gov/pubmed/34824268
http://dx.doi.org/10.1038/s41467-021-27232-5