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Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase

Cytochrome c oxidases are among the most important and fundamental enzymes of life. Integrated into membranes they use four electrons from cytochrome c molecules to reduce molecular oxygen (dioxygen) to water. Their catalytic cycle has been considered to start with the oxidized form. Subsequent elec...

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Detalles Bibliográficos
Autores principales: Kolbe, F., Safarian, S., Piórek, Ż., Welsch, S., Müller, H., Michel, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617209/
https://www.ncbi.nlm.nih.gov/pubmed/34824221
http://dx.doi.org/10.1038/s41467-021-27174-y