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Heterogeneous recruitment abilities to RNA polymerases generate nonlinear scaling of gene expression with cell volume

While most genes’ expression levels are proportional to cell volumes, some genes exhibit nonlinear scaling between their expression levels and cell volume. Therefore, their mRNA and protein concentrations change as the cell volume increases, which often have crucial biological functions such as cell...

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Detalles Bibliográficos
Autores principales: Wang, Qirun, Lin, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617254/
https://www.ncbi.nlm.nih.gov/pubmed/34824198
http://dx.doi.org/10.1038/s41467-021-26952-y