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Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development

During ovarian follicular development, granulosa cells proliferate and progressively differentiate to support oocyte maturation and ovulation. To determine the underlying links between proliferation and differentiation in granulosa cells, we determined changes in 1) the expression of genes regulatin...

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Detalles Bibliográficos
Autores principales: Kawai, Tomoko, Richards, JoAnne S., Shimada, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617273/
https://www.ncbi.nlm.nih.gov/pubmed/34824385
http://dx.doi.org/10.1038/s42003-021-02849-w