Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance

Maternal obesity (MO) predisposes offspring to obesity and metabolic disorders but little is known about the contribution of offspring brown adipose tissue (BAT). We find that MO impairs fetal BAT development, which persistently suppresses BAT thermogenesis and primes female offspring to metabolic d...

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Detalles Bibliográficos
Autores principales: Chen, Yan-Ting, Yang, Qi-Yuan, Hu, Yun, Liu, Xiang-Dong, de Avila, Jeanene M., Zhu, Mei-Jun, Nathanielsz, Peter W., Du, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617289/
https://www.ncbi.nlm.nih.gov/pubmed/34824246
http://dx.doi.org/10.1038/s41467-021-27171-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617289/
https://www.ncbi.nlm.nih.gov/pubmed/34824246
http://dx.doi.org/10.1038/s41467-021-27171-1

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