THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates

Emerging antibiotic resistance demands identification of novel antibacterial compound classes. A bacterial whole-cell screen based on pneumococcal autolysin-mediated lysis induction was developed to identify potential bacterial cell wall synthesis inhibitors. A hit class comprising a 1-amino substit...

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Detalles Bibliográficos
Autores principales: Reithuber, Elisabeth, Wixe, Torbjörn, Ludwig, Kevin C., Müller, Anna, Uvell, Hanna, Grein, Fabian, Lindgren, Anders E. G., Muschiol, Sandra, Nannapaneni, Priyanka, Eriksson, Anna, Schneider, Tanja, Normark, Staffan, Henriques-Normark, Birgitta, Almqvist, Fredrik, Mellroth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617507/
https://www.ncbi.nlm.nih.gov/pubmed/34785593
http://dx.doi.org/10.1073/pnas.2108244118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617507/
https://www.ncbi.nlm.nih.gov/pubmed/34785593
http://dx.doi.org/10.1073/pnas.2108244118

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