Quantitative assessment reveals the dominance of duplicated sequences in germline-derived extrachromosomal circular DNA

Extrachromosomal circular DNA (eccDNA) originates from linear chromosomal DNA in various human tissues under physiological and disease conditions. The genomic origins of eccDNA have largely been investigated using in vitro–amplified DNA. However, in vitro amplification obscures quantitative informat...

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Detalles Bibliográficos
Autores principales: Mouakkad-Montoya, Lila, Murata, Michael M., Sulovari, Arvis, Suzuki, Ryusuke, Osia, Beth, Malkova, Anna, Katsumata, Makoto, Giuliano, Armando E., Eichler, Evan E., Tanaka, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617514/
https://www.ncbi.nlm.nih.gov/pubmed/34789574
http://dx.doi.org/10.1073/pnas.2102842118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617514/
https://www.ncbi.nlm.nih.gov/pubmed/34789574
http://dx.doi.org/10.1073/pnas.2102842118

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