Powerful gene-based testing by integrating long-range chromatin interactions and knockoff genotypes

Gene-based tests are valuable techniques for identifying genetic factors in complex traits. Here, we propose a gene-based testing framework that incorporates data on long-range chromatin interactions, several recent technical advances for region-based tests, and leverages the knockoff framework for...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Shiyang, Dalgleish, James, Lee, Justin, Wang, Chen, Liu, Linxi, Gill, Richard, Buxbaum, Joseph D., Chung, Wendy K., Aschard, Hugues, Silverman, Edwin K., Cho, Michael H., He, Zihuai, Ionita-Laza, Iuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617518/
https://www.ncbi.nlm.nih.gov/pubmed/34799441
http://dx.doi.org/10.1073/pnas.2105191118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617518/
https://www.ncbi.nlm.nih.gov/pubmed/34799441
http://dx.doi.org/10.1073/pnas.2105191118

Ejemplares similares