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Powerful gene-based testing by integrating long-range chromatin interactions and knockoff genotypes

Gene-based tests are valuable techniques for identifying genetic factors in complex traits. Here, we propose a gene-based testing framework that incorporates data on long-range chromatin interactions, several recent technical advances for region-based tests, and leverages the knockoff framework for...

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Detalles Bibliográficos
Autores principales:	Ma, Shiyang, Dalgleish, James, Lee, Justin, Wang, Chen, Liu, Linxi, Gill, Richard, Buxbaum, Joseph D., Chung, Wendy K., Aschard, Hugues, Silverman, Edwin K., Cho, Michael H., He, Zihuai, Ionita-Laza, Iuliana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617518/ https://www.ncbi.nlm.nih.gov/pubmed/34799441 http://dx.doi.org/10.1073/pnas.2105191118

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