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Biological function and molecular mechanism of SRSF3 in cancer and beyond

Serine/arginine-rich splicing factor 3 (SRSF3; also known as SRp20), an important member of the family of SRSFs, is abnormally expressed in tumors, resulting in aberrant splicing of hub genes, such as CD44, HER2, MDM4, Rac family small GTPase 1 and tumor protein p53. Under normal conditions, the spl...

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Detalles Bibliográficos
Autores principales: Xiong, Jian, Chen, Yinshuang, Wang, Weipeng, Sun, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617561/
https://www.ncbi.nlm.nih.gov/pubmed/34858525
http://dx.doi.org/10.3892/ol.2021.13139