Systematic measurement of combination-drug landscapes to predict in vivo treatment outcomes for tuberculosis

Lengthy multidrug chemotherapy is required to achieve a durable cure in tuberculosis. However, we lack well-validated, high-throughput in vitro models that predict animal outcomes. Here, we provide an extensible approach to rationally prioritize combination therapies for testing in in vivo mouse mod...

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Detalles Bibliográficos
Autores principales: Larkins-Ford, Jonah, Greenstein, Talia, Van, Nhi, Degefu, Yonatan N., Olson, Michaela C., Sokolov, Artem, Aldridge, Bree B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617591/
https://www.ncbi.nlm.nih.gov/pubmed/34469743
http://dx.doi.org/10.1016/j.cels.2021.08.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617591/
https://www.ncbi.nlm.nih.gov/pubmed/34469743
http://dx.doi.org/10.1016/j.cels.2021.08.004

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