MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants

Untreated familial hypercholesterolemia (FH) leads to atherosclerosis and early cardiovascular disease. Mutations in the low-density lipoprotein receptor (LDLr) gene constitute the major cause of FH, and the high number of mutations already described in the LDLr makes necessary cascade screening or...

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Detalles Bibliográficos
Autores principales: Larrea-Sebal, Asier, Benito-Vicente, Asier, Fernandez-Higuero, José A., Jebari-Benslaiman, Shifa, Galicia-Garcia, Unai, Uribe, Kepa B., Cenarro, Ana, Ostolaza, Helena, Civeira, Fernando, Arrasate, Sonia, González-Díaz, Humberto, Martín, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617597/
https://www.ncbi.nlm.nih.gov/pubmed/34869944
http://dx.doi.org/10.1016/j.jacbts.2021.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617597/
https://www.ncbi.nlm.nih.gov/pubmed/34869944
http://dx.doi.org/10.1016/j.jacbts.2021.08.009

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