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β-Arrestin–Mediated Angiotensin II Type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is a disease of abnormal pulmonary vascular remodeling whose medical therapies are thought to primarily act as vasodilators but also may have effects on pulmonary vascular remodeling. The angiotensin II type 1 receptor (AT(1)R) is a G protein–coupled receptor th...

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Detalles Bibliográficos
Autores principales: Ma, Zhiyuan, Viswanathan, Gayathri, Sellig, Mason, Jassal, Chanpreet, Choi, Issac, Garikipati, Aditi, Xiong, Xinyu, Nazo, Nour, Rajagopal, Sudarshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617598/
https://www.ncbi.nlm.nih.gov/pubmed/34869949
http://dx.doi.org/10.1016/j.jacbts.2021.09.006