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Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome

Down syndrome (DS) is a complex genetic disorder associated with substantial physical, cognitive, and behavioral challenges. Due to better treatment options for the physical co-morbidities of DS, the life expectancy of individuals with DS is beginning to approach that of the general population. Howe...

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Detalles Bibliográficos
Autores principales: Stensen, Wenche, Rothweiler, Ulli, Engh, Richard Alan, Stasko, Melissa R., Bederman, Ilya, Costa, Alberto C. S., Fugelli, Anders, Svendsen, John S. Mjøen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617627/
https://www.ncbi.nlm.nih.gov/pubmed/34832952
http://dx.doi.org/10.3390/ph14111170