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High Glucose Reduces the Paracellular Permeability of the Submandibular Gland Epithelium via the MiR-22-3p/Sp1/Claudin Pathway

Tight junctions (TJs) play an important role in water, ion, and solute transport through the paracellular pathway of epithelial cells; however, their role in diabetes-induced salivary gland dysfunction remains unknown. Here, we found that the TJ proteins claudin-1 and claudin-3 were significantly in...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Liu, Hui-Min, Mao, Qian-Ying, Cong, Xin, Zhang, Yan, Lee, Sang-Woo, Park, Kyungpyo, Wu, Li-Ling, Xiang, Ruo-Lan, Yu, Guang-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617860/
https://www.ncbi.nlm.nih.gov/pubmed/34831451
http://dx.doi.org/10.3390/cells10113230