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Interaction between M. tuberculosis Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB

Tuberculosis (TB) remains a major public health threat globally, especially in sub-Saharan Africa. Both human and Mycobacterium tuberculosis (MTBC) genetic variation affect TB outcomes, but few studies have examined if and how the two genomes interact to affect disease. We hypothesize that long-term...

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Detalles Bibliográficos
Autores principales: McHenry, Michael L., Wampande, Eddie M., Joloba, Moses L., Malone, LaShaunda L., Mayanja-Kizza, Harriet, Bush, William S., Boom, W. Henry, Williams, Scott M., Stein, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617877/
https://www.ncbi.nlm.nih.gov/pubmed/34832643
http://dx.doi.org/10.3390/pathogens10111487