A Free-Energy Landscape Analysis of Calmodulin Obtained from an NMR Data-Utilized Multi-Scale Divide-and-Conquer Molecular Dynamics Simulation

Calmodulin (CaM) is a multifunctional calcium-binding protein, which regulates a variety of biochemical processes. CaM acts through its conformational changes and complex formation with its target enzymes. CaM consists of two globular domains (N-lobe and C-lobe) linked by an extended linker region....

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Detalles Bibliográficos
Autores principales: Shimoyama, Hiromitsu, Shigeta, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617919/
https://www.ncbi.nlm.nih.gov/pubmed/34833117
http://dx.doi.org/10.3390/life11111241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617919/
https://www.ncbi.nlm.nih.gov/pubmed/34833117
http://dx.doi.org/10.3390/life11111241

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