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Stabilization by Nano Spray Dryer of Pioglitazone Polymeric Nanosystems: Development, In Vivo, Ex Vivo and Synchrotron Analysis

Pioglitazone-loaded PLGA-PEG nanoparticles (NPs) were stabilized by the spray drying technique as an alternative to the treatment of ocular inflammatory disorders. Pioglitazone-NPs were developed and characterized physiochemically. Interaction studies, biopharmaceutical behavior, ex vivo corneal and...

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Detalles Bibliográficos
Autores principales: Silva-Abreu, Marcelle, Miralles, Esther, Kamma-Lorger, Christina S., Espina, Marta, García, María Luisa, Calpena, Ana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617923/
https://www.ncbi.nlm.nih.gov/pubmed/34834165
http://dx.doi.org/10.3390/pharmaceutics13111751