Deletion of the Stress Response Gene DDR48 from Histoplasma capsulatum Increases Sensitivity to Oxidative Stress, Increases Susceptibility to Antifungals, and Decreases Fitness in Macrophages

The stress response gene DDR48 has been characterized in Saccharomyces cerevisiae and Candida albicans to be involved in combating various cellular stressors, from oxidative agents to antifungal compounds. Surprisingly, the biological function of DDR48 has yet to be identified, though it is likely a...

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Detalles Bibliográficos
Autores principales: Blancett, Logan T., Runge, Kauri A., Reyes, Gabriella M., Kennedy, Lauren A., Jackson, Sydney C., Scheuermann, Sarah E., Harmon, Mallory B., Williams, Jamease C., Shearer, Glenmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617954/
https://www.ncbi.nlm.nih.gov/pubmed/34829268
http://dx.doi.org/10.3390/jof7110981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617954/
https://www.ncbi.nlm.nih.gov/pubmed/34829268
http://dx.doi.org/10.3390/jof7110981

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