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Deletion of the Stress Response Gene DDR48 from Histoplasma capsulatum Increases Sensitivity to Oxidative Stress, Increases Susceptibility to Antifungals, and Decreases Fitness in Macrophages
The stress response gene DDR48 has been characterized in Saccharomyces cerevisiae and Candida albicans to be involved in combating various cellular stressors, from oxidative agents to antifungal compounds. Surprisingly, the biological function of DDR48 has yet to be identified, though it is likely a...
Autores principales: | Blancett, Logan T., Runge, Kauri A., Reyes, Gabriella M., Kennedy, Lauren A., Jackson, Sydney C., Scheuermann, Sarah E., Harmon, Mallory B., Williams, Jamease C., Shearer, Glenmore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617954/ https://www.ncbi.nlm.nih.gov/pubmed/34829268 http://dx.doi.org/10.3390/jof7110981 |
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