Population Pharmacokinetic Analysis and Dosing Optimization of Prophylactic Fluconazole in Japanese Patients with Hematological Malignancy

We conducted population pharmacokinetic (PPK) analysis and Monte Carlo simulations to determine the appropriate prophylactic dose of fluconazole to prevent invasive candidiasis in patients with hematological malignancies. Patients receiving chemotherapy or hematopoietic stem cell transplantation at...

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Detalles Bibliográficos
Autores principales: Sakamoto, Yasutaka, Isono, Hikaru, Enoki, Yuki, Taguchi, Kazuaki, Miyazaki, Takuya, Kunimoto, Hiroyoshi, Koike, Hirofumi, Hagihara, Maki, Matsumoto, Kenji, Nakajima, Hideaki, Sahashi, Yukiko, Matsumoto, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618010/
https://www.ncbi.nlm.nih.gov/pubmed/34829262
http://dx.doi.org/10.3390/jof7110975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618010/
https://www.ncbi.nlm.nih.gov/pubmed/34829262
http://dx.doi.org/10.3390/jof7110975

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