Cladribine Alters Immune Cell Surface Molecules for Adhesion and Costimulation: Further Insights to the Mode of Action in Multiple Sclerosis

Cladribine (CLAD) is a deoxyadenosine analogue prodrug which is given in multiple sclerosis (MS) as two short oral treatment courses 12 months apart. Reconstitution of adaptive immune function following selective immune cell depletion is the presumed mode of action. In this exploratory study, we inv...

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Detalles Bibliográficos
Autores principales: Moser, Tobias, Hoepner, Lena, Schwenker, Kerstin, Seiberl, Michael, Feige, Julia, Akgün, Katja, Haschke-Becher, Elisabeth, Ziemssen, Tjalf, Sellner, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618022/
https://www.ncbi.nlm.nih.gov/pubmed/34831335
http://dx.doi.org/10.3390/cells10113116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618022/
https://www.ncbi.nlm.nih.gov/pubmed/34831335
http://dx.doi.org/10.3390/cells10113116

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