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RNA-Seq Analysis Reveals an Essential Role of the Tyrosine Metabolic Pathway and Inflammation in Myopia-Induced Retinal Degeneration in Guinea Pigs

Background: Myopia is the second leading cause of visual impairment globally. Myopia can induce sight-threatening retinal degeneration and the underlying mechanism remains poorly defined. We generated a model of myopia-induced early-stage retinal degeneration in guinea pigs and investigated the mech...

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Detalles Bibliográficos
Autores principales: Zeng, Ling, Li, Xiaoning, Liu, Jian, Liu, Hong, Xu, Heping, Yang, Zhikuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618104/
https://www.ncbi.nlm.nih.gov/pubmed/34830490
http://dx.doi.org/10.3390/ijms222212598