Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence

Disease relapse and therapy resistance remain key challenges in treating multiple myeloma. Underlying (epi-)mutational events can promote myelomagenesis and contribute to multi-drug and apoptosis resistance. Therefore, compounds inducing ferroptosis, a form of iron and lipid peroxidation-regulated c...

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Detalles Bibliográficos
Autores principales: Logie, Emilie, Van Puyvelde, Bart, Cuypers, Bart, Schepers, Anne, Berghmans, Herald, Verdonck, Jelle, Laukens, Kris, Godderis, Lode, Dhaenens, Maarten, Deforce, Dieter, Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618106/
https://www.ncbi.nlm.nih.gov/pubmed/34830117
http://dx.doi.org/10.3390/ijms222212234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618106/
https://www.ncbi.nlm.nih.gov/pubmed/34830117
http://dx.doi.org/10.3390/ijms222212234

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