Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain

Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the viral nucleoprotein (NP) and double-stranded RNA for viral RNA transcription/replication and inhibition of type I interfero...

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Detalles Bibliográficos
Autores principales: Kasajima, Nodoka, Matsuno, Keita, Miyamoto, Hiroko, Kajihara, Masahiro, Igarashi, Manabu, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618116/
https://www.ncbi.nlm.nih.gov/pubmed/34835122
http://dx.doi.org/10.3390/v13112316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618116/
https://www.ncbi.nlm.nih.gov/pubmed/34835122
http://dx.doi.org/10.3390/v13112316

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