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In Vivo Modelling of Hepatitis B Virus Subgenotype A1 Replication Using Adeno-Associated Viral Vectors

The paucity of animal models that simulate the replication of the hepatitis B virus (HBV) is an impediment to advancing new anti-viral treatments. The work reported here employed recombinant adeno-associated viruses (AAVs) to model HBV subgenotype A1 and subgenotype D3 replication in vitro and in vi...

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Detalles Bibliográficos
Autores principales: Limani, Shonisani Wendy, Mnyandu, Njabulo, Ely, Abdullah, Wadee, Reubina, Kramvis, Anna, Arbuthnot, Patrick, Maepa, Mohube Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618177/
https://www.ncbi.nlm.nih.gov/pubmed/34835053
http://dx.doi.org/10.3390/v13112247