Cargando…

A Multifunctional Polymeric Micelle for Targeted Delivery of Paclitaxel by the Inhibition of the P-Glycoprotein Transporters

P-glycoprotein (P-gP) efflux-mediated multidrug resistance is a fundamental aspect of chemotherapeutic failure in oncology. The current study aims to deliver paclitaxel (PTX) specifically at the target site with improved in vivo efficacy of poorly permeable PTX against solid tumors. Multifunctional...

Descripción completa

Detalles Bibliográficos
Autores principales: Razzaq, Sobia, Rauf, Aisha, Raza, Abida, Akhtar, Sohail, Tabish, Tanveer A., Sandhu, Mansur Abdullah, Zaman, Muhammad, Ibrahim, Ibrahim M., Shahnaz, Gul, Rahdar, Abbas, Díez-Pascual, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618187/
https://www.ncbi.nlm.nih.gov/pubmed/34835622
http://dx.doi.org/10.3390/nano11112858