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Effects of 5′,8′-Cyclo-2′-Deoxypurines on the Base Excision Repair of Clustered DNA Lesions in Nuclear Extracts of the XPC Cell Line

Clustered DNA lesions (CDL) containing 5′,8-cyclo-2′-deoxypurines (cdPus) are an example of extensive abnormalities occurring in the DNA helix and may impede cellular repair processes. The changes in the efficiency of nuclear base excision repair (BER) were investigated using (a) two cell lines, one...

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Detalles Bibliográficos
Autores principales: Kaźmierczak-Barańska, Julia, Boguszewska, Karolina, Szewczuk, Michał, Karwowski, Bolesław T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618216/
https://www.ncbi.nlm.nih.gov/pubmed/34831476
http://dx.doi.org/10.3390/cells10113254