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A Water-Soluble Polyacid Polymer Based on Hydrophilic Metal–Organic Frameworks Using Amphoteric Carboxylic Acid Ligands as Linkers for Hydroxycamptothecin Loading and Release In Vitro

The poor water solubility and severe side effects of hydroxycamptothecin (HCPT) limit its clinical application; therefore, it is necessary to synthesize applicable nanodrug carriers with good solubility to expand the applications of HCPT. In this study, a hydrophilic metal–organic framework (MOF) wi...

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Detalles Bibliográficos
Autores principales: Shi, Yuqiong, Liu, Wei, Wu, Xiangrong, Zhu, Jinhua, Zhou, Danyang, Liu, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618358/
https://www.ncbi.nlm.nih.gov/pubmed/34835619
http://dx.doi.org/10.3390/nano11112854