Cross Pharmacological, Biochemical and Computational Studies of a Human Kv3.1b Inhibitor from Androctonus australis Venom

The voltage-gated K(+) channels Kv3.1 display fast activation and deactivation kinetics and are known to have a crucial contribution to the fast-spiking phenotype of certain neurons. AahG50, as a natural product extracted from Androctonus australis hector venom, inhibits selectively Kv3.1 channels....

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Detalles Bibliográficos
Autores principales: Maatoug, Sonia, Cheikh, Amani, Khamessi, Oussema, Tabka, Hager, Landoulsi, Zied, Guigonis, Jean-Marie, Diochot, Sylvie, Bendahhou, Saïd, Benkhalifa, Rym
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618407/
https://www.ncbi.nlm.nih.gov/pubmed/34830172
http://dx.doi.org/10.3390/ijms222212290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618407/
https://www.ncbi.nlm.nih.gov/pubmed/34830172
http://dx.doi.org/10.3390/ijms222212290

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