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Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice

The kidney is one of the most susceptible organs to age-related impairments. Generally, renal aging is accompanied by renal fibrosis, which is the final common pathway of chronic kidney diseases. Aristolochic acid (AA), a nephrotoxic agent, causes AA nephropathy (AAN), which is characterized by prog...

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Detalles Bibliográficos
Autores principales: Urate, Shingo, Wakui, Hiromichi, Azushima, Kengo, Yamaji, Takahiro, Suzuki, Toru, Abe, Eriko, Tanaka, Shohei, Taguchi, Shinya, Tsukamoto, Shunichiro, Kinguchi, Sho, Uneda, Kazushi, Kanaoka, Tomohiko, Atobe, Yoshitoshi, Funakoshi, Kengo, Yamashita, Akio, Tamura, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618437/
https://www.ncbi.nlm.nih.gov/pubmed/34830314
http://dx.doi.org/10.3390/ijms222212432