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The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation

The addition of glycerol to protein solutions is often used to hinder the aggregation and denaturation of proteins. However, it is not a generalised practice against chemical degradation reactions. The chemical degradation of proteins, such as deamidation and isomerisation, is an important deteriora...

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Detalles Bibliográficos
Autores principales: Ramm, Ingrid, Sanchez-Fernandez, Adrian, Choi, Jaeyeong, Lang, Christian, Fransson, Jonas, Schagerlöf, Herje, Wahlgren, Marie, Nilsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618440/
https://www.ncbi.nlm.nih.gov/pubmed/34834267
http://dx.doi.org/10.3390/pharmaceutics13111853