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The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation
The addition of glycerol to protein solutions is often used to hinder the aggregation and denaturation of proteins. However, it is not a generalised practice against chemical degradation reactions. The chemical degradation of proteins, such as deamidation and isomerisation, is an important deteriora...
Autores principales: | Ramm, Ingrid, Sanchez-Fernandez, Adrian, Choi, Jaeyeong, Lang, Christian, Fransson, Jonas, Schagerlöf, Herje, Wahlgren, Marie, Nilsson, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618440/ https://www.ncbi.nlm.nih.gov/pubmed/34834267 http://dx.doi.org/10.3390/pharmaceutics13111853 |
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