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Establishment and Characterization of NCC-DDLPS4-C1: A Novel Patient-Derived Cell Line of Dedifferentiated Liposarcoma

Dedifferentiated liposarcoma (DDLPS) is a highly malignant sarcoma characterized by the co-amplification of MDM2 and CDK4. Although systemic chemotherapy is recommended for unresectable or metastatic cases, DDLPS is insensitive to conventional chemotherapy, leading to an unfavorable prognosis. There...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Ryuto, Yoshimatsu, Yuki, Noguchi, Rei, Sin, Yooksil, Ono, Takuya, Akiyama, Taro, Hirose, Takeshi, Iwata, Shintaro, Yoshida, Akihiko, Ohtori, Seiji, Kawai, Akira, Kondo, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618493/
https://www.ncbi.nlm.nih.gov/pubmed/34834427
http://dx.doi.org/10.3390/jpm11111075