Host Protease Activity on Bacterial Pathogens Promotes Complement and Antibiotic-Directed Killing

Our understanding of how the host immune system thwarts bacterial evasive mechanisms remains incomplete. Here, we show that host protease neutrophil elastase acts on Acinetobacter baumannii and Pseudomonas aeruginosa to destroy factors that prevent serum-associated, complement-directed killing. The...

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Detalles Bibliográficos
Autores principales: Chen, Shaorong, Zhang, Dongmei, Roberts, Alexandria-Jade, Lu, Hsueh-Chung, Cannon, Carolyn L., Qin, Qing-Ming, de Figueiredo, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618517/
https://www.ncbi.nlm.nih.gov/pubmed/34832660
http://dx.doi.org/10.3390/pathogens10111506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618517/
https://www.ncbi.nlm.nih.gov/pubmed/34832660
http://dx.doi.org/10.3390/pathogens10111506

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