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Host Protease Activity on Bacterial Pathogens Promotes Complement and Antibiotic-Directed Killing
Our understanding of how the host immune system thwarts bacterial evasive mechanisms remains incomplete. Here, we show that host protease neutrophil elastase acts on Acinetobacter baumannii and Pseudomonas aeruginosa to destroy factors that prevent serum-associated, complement-directed killing. The...
Autores principales: | Chen, Shaorong, Zhang, Dongmei, Roberts, Alexandria-Jade, Lu, Hsueh-Chung, Cannon, Carolyn L., Qin, Qing-Ming, de Figueiredo, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618517/ https://www.ncbi.nlm.nih.gov/pubmed/34832660 http://dx.doi.org/10.3390/pathogens10111506 |
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