Two Novel Precursors of the HIV-1 Protease Inhibitor Darunavir Target the UPR/Proteasome System in Human Hepatocellular Carcinoma Cell Line HepG2

Background: Several pre-clinical and clinical reports suggest that HIV-1 protease inhibitors, in addition to the antiretroviral properties, possess pleiotropic pharmacological effects including anticancer action. Therefore, we investigated the pro-apoptotic activity in tumor cells of two molecules,...

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Detalles Bibliográficos
Autores principales: Rinaldi, Roberta, Miglionico, Rocchina, Nigro, Ilaria, D’Orsi, Rosarita, Chiummiento, Lucia, Funicello, Maria, Lupattelli, Paolo, Laurenzana, Ilaria, Sgambato, Alessandro, Monné, Magnus, Bisaccia, Faustino, Armentano, Maria Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618555/
https://www.ncbi.nlm.nih.gov/pubmed/34831275
http://dx.doi.org/10.3390/cells10113052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618555/
https://www.ncbi.nlm.nih.gov/pubmed/34831275
http://dx.doi.org/10.3390/cells10113052

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